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Banning Avandia would give Washington another political scalp

Friday, July 16th, 2010

9% of the U.S. population suffers from Type 2 diabetes and for many patients and their physicians the benefits of controlling blood sugar levels outweigh the risks of drugs on the market like Avandia.  According to an editorial in today’s Wall Street Journal; The Cleveland Clinic cardiologist and pharma scourge Steven Nissen fired the starting pistol in 2007 with a “meta analysis” that showed cardiac risks that weren’t reflected in any of the many data from separate clinical trials he analyzed

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Weekly Roundup – 3/4/10

Friday, March 5th, 2010

We creep closer to Spring.

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Dimebon Comes Crashing to Earth

Wednesday, March 3rd, 2010

Earlier this month I wrote about Medivation and their Russian-derived clinical candidate for Alzheimer’s disease, Dimebon (latrepirdine). At the time, I wrote that “A lot of eye-catching numbers from small Phase II trials tend to flatten out in the wider world of Phase III, and if forced, that’s the way I’d bet here.” Unfortunately, that’s just what appears to have happened . The results are out today, and Dimebon has not showed any efficacy at all versus placebo

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Content marketing: When will the drug industry get it ?

Monday, March 1st, 2010

Although marketing is changing because of new consumer behavior one aspect of marketing remains the same: go where your audience is. While there are more and more people using the Web for health information there has also been an explosion of health sites and social media on the Internet. There are, for example, over 1,000 pages of health related information on Facebook.

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Should pharma Tweet?

Wednesday, January 20th, 2010

Facts presented in evidence: 1. Twitter demographics: Only 9% of people aged 50-62 use Twitter according to eMarketer (see below)

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Recommended Books For Medicinal Chemists, Part One

Monday, November 23rd, 2009

I asked recently for suggestions on the best books on med-chem topics, and a lot of good ideas came in via the comments and e-mail. Going over the list, the most recommended seem to be the following: For general medicinal chemistry, you have Bob Rydzewski’s Real World Drug Discovery: A Chemist’s Guide to Biotech and Pharmaceutical Research

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FDA’s Plan for Risk Communication, Part 2

Monday, October 26th, 2009

In a document released this Fall, the FDA laid out its Strategic Plan for Risk Communication .

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Engineering Receptors: Not Quite There Yet. Not Exactly.

Friday, October 16th, 2009

There have been several reports over the years of people engineering receptor proteins to make them do defined tasks. They’ve generally been using the bacterial periplasmic binding proteins (PBPs) as a starting point, attaching some sort of fluorescent group onto one end, so that when a desired ligand binds, the protein folds in on itself in a way to set off a fluorescent resonance energy transfer (FRET)

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Right Where You Want Them

Tuesday, September 8th, 2009

Imagine a drug molecule, and imagine it’s a really good one. That is, it’s made it out of the gut just fine, out into the bloodstream, and it’s even slipped in through the membrane of the targeted cells.

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TreeHouse – Bed

Friday, September 4th, 2009

The longer a child with autism goes without help, the harder they are to reach. Agency: CHI & Partners, London, UK Creative Director: Ewan Paterson Creative team: Alan Cinnamond and Sandy Cinnamond Photographer: Tim McPherson Typographer and Designer: Craig Ward Brand name: Talk about autism Generic name/category: public service, disease awareness Brand name: Treehouse Country/Market: UK, Europe Indication(s)/use: autism Target: Consumers (DTC) Tagline: The longer a child with autism goes without help, the harder they are to reach. Medium: Print ad Size/duration: double-page spread, poster Publication/Aired: August 2009 To see all of this brand's ads on AdPharm, click here 0 views Sep 04, 2009 Visit AdPharm.net for more pharmaceutical ads

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